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Efficient Asymmetry Generation in the Synthesis of Oxo‐Rhenium( V ) Complex cis ‐[ReOCl 2 {OCMe 2 CMe 2 OP(OCMe 2 CMe 2 O)}py]
Author(s) -
Rybak Witold K.,
Skarżyńska Anna,
Głowiak Tadeusz
Publication year - 2003
Publication title -
angewandte chemie international edition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 1433-7851
DOI - 10.1002/anie.200219501
Subject(s) - rhenium , enantiomer , crystallization , autocatalysis , chemistry , chirality (physics) , asymmetry , enantiomeric excess , circular dichroism , spectroscopy , enantioselective synthesis , stereochemistry , crystallography , combinatorial chemistry , organic chemistry , catalysis , symmetry breaking , physics , chiral symmetry breaking , quantum mechanics , nambu–jona lasinio model
Its all done without mirrors : A simple procedure that randomly produces enantiomers of an oxo‐rhenium( V ) complex with a large enantiomeric excess (99 % ee ) from optically inactive precursors is presented. The chirally autocatalytic synthesis is achieved by the spontaneous resolution of the conglomerate in a stirred crystallization following the formation of the complex in the reaction system. The results are supported by circular dichroism spectroscopy (see picture).