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Intramolecular Hydrocarbonation of α‐Alkynyl Malononitriles Catalyzed by Palladium Olefin Complexes
Author(s) -
Tsukada Naofumi,
Yamamoto Yoshinori
Publication year - 1997
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199724771
Subject(s) - intramolecular force , catalysis , chemistry , palladium , olefin fiber , medicinal chemistry , combinatorial chemistry , organic chemistry
A [(cod)Pd 0 ] species is the catalyst for the title reaction. ε‐Alkynyl malononitriles 1 cyclize selectively in the process to give ( Z )‐alkylidenecyclopentanes 2 in good to very good yields. Phosphanepalladium complexes are significantly less effective in this reacton than alkenepalladium compounds. cod = 1,5‐cyclooctadiene.