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Charge Transfer in DNA: A Controversy
Author(s) -
Diederichsen Ulf
Publication year - 1997
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199723171
Subject(s) - stacking , dna , electron transfer , charge (physics) , stack (abstract data type) , transfer (computing) , schematic , base pair , chemistry , chemical physics , biophysics , physics , genetics , computer science , biology , electrical engineering , engineering , quantum mechanics , photochemistry , parallel computing , programming language , organic chemistry
Electron transfer over distances of more than 40 Å through a DNA double strand (see schematic representation on the right) still stimulates controversy about mechanism but seems to be proven experimentally. Biochemical processes such as repair of photodimer damage can be initiated by DNA electron transfer. The dependence of electron transport on how nearly perfect a DNA base stack is suggests that conductivity can be used to quantify stacking quality or to recognize a DNA single strand.