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Evidence for Directed Metalation: A Structural Intermediate in the Formation of a Novel C‐bound Adenine Complex of Ruthenium
Author(s) -
Price Clayton,
Elsegood Mark R. J.,
Clegg William,
Rees Nicholas H.,
Houlton Andrew
Publication year - 1997
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199717621
Subject(s) - nucleobase , ethylenediamine , metalation , chemistry , ruthenium , ligand (biochemistry) , denticity , stereochemistry , conjugate , combinatorial chemistry , crystallography , dna , crystal structure , catalysis , receptor , inorganic chemistry , organic chemistry , mathematics , biochemistry , mathematical analysis
The nucleobase–ligand conjugate from ethylenediamine and 9‐ethyladenine can function as a bidentate or tridentate ligand to Ru II . Both modes of coordination involve the ethylenediamine group, while the latter additionally relies on carbonmetal bond formation through C 8 of the nucleobase (structure depicted on the right).