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A Hydrogen‐Bonding Receptor That Binds Urea with High Affinity
Author(s) -
Bell Thomas W.,
Hou Zheng
Publication year - 1997
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199715361
Subject(s) - urea , hydrogen bond , chemistry , recrystallization (geology) , receptor , acceptor , thermal stability , crystallography , molecule , biochemistry , organic chemistry , biology , paleontology , physics , condensed matter physics
All the conceivable donor and acceptor sites of urea are involved in hydrogen bonds in the complex with the highly preorganized artificial receptor 1 . The resulting complex is so stable that it can be purified by thermal recrystallization from pure DMSO; a stability constant of 1.4 × 10 4 M −1 has been estimated from the urea‐selective UV/Vis response of this receptor.