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Cover Picture (Angew. Chem. Int. Ed. Engl. 8/1997)
Publication year - 1997
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199707891
Subject(s) - steric effects , cover (algebra) , chemistry , stereochemistry , library science , crystallography , art history , computer science , art , engineering , mechanical engineering
The cover picture shows the structural formulas in red of citrate and a synthetic receptor that is selective for binding citrate in aqueous media. The center picture is the structure of the host–guest complex, derived by molecular mechanics, that was patterned after the crystal structure of the receptor and tricarballate. The receptor is preorganized for citrate recognition because of the alternation of steric interactions around the benzene ring. Selectivity for citrate was demonstrated in competition experiments. Further, the receptor can be used to bind citrate in juices, as is highlighted by the pictures of fruit. More on the recognition properties and synthesis of this receptor is reported by E. V Anslyn et al. on pp. 862. (Graphics developed with assistance from B. Iverson at the University of Texas at Austin.)