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Combinatorial Chemistry with Laser Optical Encoding
Author(s) -
Xiao Xiaoyi,
Zhao Chanfeng,
Potash Hanan,
Nova Michael P.
Publication year - 1997
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199707801
Subject(s) - sorting , oligonucleotide , solid phase synthesis , combinatorial chemistry , laser , combinatorial synthesis , chemistry , characterization (materials science) , encoding (memory) , materials science , nanotechnology , computer science , optics , algorithm , physics , dna , biochemistry , peptide , artificial intelligence
A new strategy for solid‐phase combinatorial synthesis : Application of laser optical synthesis chips (shown schematically on the right; other end groups include OH, COOH, and Cl) and directed sorting allows formation and reliable characterization of libraries of small organic molecules, peptides, and oligonucleotides.