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Enantioselective Hydrogen Transfer from a Chiral Tin Hydride to a Prochiral Carbon‐Centered Radical
Author(s) -
Blumenstein Michael,
Schwarzkopf Kay,
Metzger Jürgen O.
Publication year - 1997
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199702351
Subject(s) - tin , enantioselective synthesis , hydride , hydrogen , carbon fibers , chemistry , materials science , organic chemistry , catalysis , composite material , composite number
Synthetically useful enantiomeric excesses were obtained for the first time in radical reductions with optically active tin hydrides, as illustrated in the reaction of 2 with 1 [Eq. (a)]. Moreover, the reaction, the reaction can also be performed catalytically by using the appropriate tin bromide and Na[B(CN)H 3 ] instead of 1 .
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