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Chiral Heterocylic Carbenes in Asymmetric Homogeneous Catalysis
Author(s) -
Herrmann Wolfgang A.,
Goossen Lukas J.,
Köcher Christian,
Artus Georg R. J.
Publication year - 1996
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199628051
Subject(s) - hydrosilylation , acetophenone , catalysis , carbene , rhodium , ligand (biochemistry) , chemistry , homogeneous , enantioselective synthesis , homogeneous catalysis , chiral ligand , combinatorial chemistry , metal , organic chemistry , physics , thermodynamics , biochemistry , receptor
The ee values of the hydrosilylation of acetophenone with the rhodium catalyst 1 are only small; nevertheless, the robustness of the catalyst is impressive: The chiral carbene ligand, which is readily available and can be easily varied, remains bound to the metal in solution to over 100°C. Thus, no excess of ligand is necessary in the catalytic reactions.