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Achieving Stable, Reverse Water‐in‐Fluorocarbon Emulsions
Author(s) -
Sadtler Vérpnique M.,
Krafft Marie Pierre,
Riess Jean G.
Publication year - 1996
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199619761
Subject(s) - fluorocarbon , emulsion , intermolecular force , surface tension , solubility , thermal diffusivity , pulmonary surfactant , chemical engineering , materials science , polymer chemistry , chemistry , organic chemistry , thermodynamics , molecule , physics , engineering
Dispersing water in a fluorocarbon seems against nature , since two more antipathetic types of liquids, in terms of intermolecular interactions, just do not exist. Every single characteristic relevant to water‐in‐fluorocarbon reverse emulsion stability (solubility and diffusivity parameters, interfacial tension and densities) is unfavorable. Yet stable emulsions of this type can be prepared with an appropriate fluorinated surfactant. Such reverse emulsions have potential as a new class of pulmonary drug‐delivery system.