Premium
Schellman Motif in Dehydrooligopeptides: Crystal and Molecular Structure of Boc‐Val‐ΔPhe‐Leu‐Phe‐Ala‐ΔPhe‐Leu‐OMe
Author(s) -
Mal Tapas Kumar,
Jain Ratan Mani,
Chauhan Virander Singh,
Rajashankar Kanagalaghatta Ramabhatta,
Ramakumar Suryanarayanarao
Publication year - 1996
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199607651
Subject(s) - chemistry , peptide , stereochemistry , structural motif , protein secondary structure , crystal structure , crystallography , biochemistry
Secondary structural motifs found in peptides are also generated in model compounds containing α,β‐didehydrophenylalanine residues (ΔPhe). A short peptide containing two ΔPhe units, Boc‐Val‐ΔPhe‐Leu‐Phe‐Ala‐ΔPhe‐Leu‐OMe, was found to assume a 3 10 /α‐helical conformation terminated by a Schellman motif.