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A General and Efficient Method for the Monohydroxylation of Alkanes
Author(s) -
Asensio Gregorio,
Mello Rossella,
GonzálezNúñnez María Elena,
Castellano Gloria,
Corral Julia
Publication year - 1996
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199602171
Subject(s) - dioxirane , trifluoroacetic anhydride , alkyl , chemistry , aryl , primary (astronomy) , organic chemistry , trifluoroacetic acid , medicinal chemistry , physics , astronomy
The initially formed alcohols do not oxidize further when primary and secondary C‐H bonds are oxidized by dioxirane 1 in the presence of a large excess of trifluoroacetic anhydride. The reactions (a) proceed with excellent yields under very mild conditions. R = alkyl, aryl; R′ = H, alkyl, aryl.