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A New Nickel‐Catalyzed Cross‐Coupling Reaction between sp 3 Carbon Centers
Author(s) -
Devasagayaraj Arokiasamy,
Stüdemann Thomas,
Knochel Paul
Publication year - 1996
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199527231
Subject(s) - nickel , catalysis , yield (engineering) , alkyl , coupling reaction , carbon fibers , coupling (piping) , chemistry , primary (astronomy) , carbon chain , polymer chemistry , organic chemistry , medicinal chemistry , materials science , metallurgy , physics , astronomy , composite number , composite material
Polyfunctional dialkylzinc compounds and primary alkyl iodides bearing a remote double bond undergo nickel‐catalyzed cross‐coupling even at −35 °C within a few hours, as shown in the example below. The resulting polyfunctional products are formed in good yield. NMP = N ‐methyl‐2‐pyrrolidinone, acac = acetylacetonate, Piv = pivaloyl.