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Saccharide–Peptide Hybrids as Novel Oligosaccharide Mimetics
Author(s) -
Wessel Hans Peter,
Mitchell Catherine M.,
Lobato Cinta Maria,
Schmid Gérard
Publication year - 1996
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199527121
Subject(s) - tetramer , oligosaccharide , block (permutation group theory) , peptide , chemistry , amino acid , biochemistry , computational biology , combinatorial chemistry , stereochemistry , biology , enzyme , mathematics , combinatorics
Block by block the carbohydrate amino acids can be peptidically coupled to form oligosaccharide mimetics, thus providing a simple approach to a novel class of compounds that has great significance for physiological processes. The feasibility of the approach is demonstrated by the block synthesis of tetramer 1 .