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New Fluorescent Water‐Soluble Taxol Derivatives
Author(s) -
Souto André A.,
Acuña A. Ulises,
Andreu José M.,
Barasoain Isabel,
Abal Miguel,
AmatGuerri Francisco
Publication year - 1996
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199527101
Subject(s) - fluorescence , fluorescein , water soluble , chemistry , solubility , combinatorial chemistry , microtubule , biophysics , organic chemistry , biology , microbiology and biotechnology , physics , quantum mechanics
Biological activity and surprisingly good solubility in water are the properties of the fluorescein‐labeled taxol 1 that make visible the attack of the antitumor agent taxol on the microtubule system in cell cultures.