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Nucleophilic Attack on (π‐Allyl)palladium Complexes: Direction of the Attack to the Central or Terminal Carbon Atom by Ligand Control
Author(s) -
Castaño Ana M.,
Aranyos Attila,
Szabó Kálmán J.,
Bäckvall JanE.
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199525511
Subject(s) - palladium , nucleophile , regioselectivity , carbon atom , chemistry , ligand (biochemistry) , terminal (telecommunication) , carbon fibers , medicinal chemistry , atom (system on chip) , stereochemistry , catalysis , organic chemistry , materials science , ring (chemistry) , telecommunications , biochemistry , receptor , composite number , computer science , composite material , embedded system
Strongly stabilized carbon nucleophiles such as dialkyl malonates can also attack the central carbon of (π‐allyl)palladium complexes. The regiochemistry of the reaction (attack at the terminal or C2 carbon atom; see picture) is controlled by the choice of the ligands L in the palladium complex. E = CO 2 Et, L = PPh 3 , P t Bu 3 , P(OPh) 3 , etc.