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A Comparison of Enthalpies of Formation in Solution and Enthalpies for HPLC Retention for Hydrogen‐Bonded Host—Guest Complexes
Author(s) -
Zimmerman Steven C.,
Kwan WingSum
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199524041
Subject(s) - high performance liquid chromatography , host (biology) , chemistry , standard enthalpy of formation , hydrogen , phase (matter) , enthalpy , component (thermodynamics) , chromatography , thermodynamics , organic chemistry , physics , ecology , biology
From the temperature‐dependent HPLC retention of a guest or host on a chemically bonded stationary phase containing the complementary component (as shown schematically on the right), the complexation enthalpies of a series of hydrogen‐bonded host‐guest complexes can be rapidly and conveniently determined. The ΔH̊ values determined in this way agree within experimental error with the complexation enthalpies measured in free solution by traditional methods.