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Influence of Lewis Base Complexation and the Degree of Aggregation of Alkyllithium Compounds on the Ration in Which They Form Addition Products and Enolates with Ketones
Author(s) -
Luitjes Hendrikus,
Schakel Marius,
Schmitz Robert F.,
Klumpp Gerhard W.
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199521521
Subject(s) - chemistry , lewis acids and bases , adduct , tetramer , base (topology) , degree (music) , nitrogen , medicinal chemistry , organic chemistry , polymer chemistry , catalysis , mathematics , acoustics , mathematical analysis , physics , enzyme
The difference between 1 and 2 lies only in the number of nitrogen atoms and not in the carbanionic unit. Since 1 , which is a tetramer, reacts with ketones to form adducts almost exclusively, but 2 virtually only enolates, the type of product formed is linked to the degree of aggregation, which in turn depends on the Lewis base.