Premium
Synthesis and Properties of First to Third Generation Dendrimers with Doubly and Triply Branched Chiral Building Blocks
Author(s) -
Murer Peter,
Seebach Dieter
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199521161
Subject(s) - dendrimer , bromide , triol , chemistry , diastereomer , combinatorial chemistry , stereochemistry , polymer chemistry , organic chemistry , diol
Dendrimers with chiral branch components and chiral central units display remarkable CD effects. An interesting case of diastereoselectivity occurs in the synthesis of these compounds: The branch bromide 1 with ( S ) configuration at the four nonspecific centers can be coupled with the triol 2 ; the ( R ) branch bromide 1 , on the other hand, cannot!
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom