Premium
Synthesis and Properties of First to Third Generation Dendrimers with Doubly and Triply Branched Chiral Building Blocks
Author(s) -
Murer Peter,
Seebach Dieter
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199521161
Subject(s) - dendrimer , bromide , triol , chemistry , diastereomer , combinatorial chemistry , stereochemistry , polymer chemistry , organic chemistry , diol
Dendrimers with chiral branch components and chiral central units display remarkable CD effects. An interesting case of diastereoselectivity occurs in the synthesis of these compounds: The branch bromide 1 with ( S ) configuration at the four nonspecific centers can be coupled with the triol 2 ; the ( R ) branch bromide 1 , on the other hand, cannot!