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Carbene Complex Functionalized Sugars
Author(s) -
Dötz Karl Heinz,
Straub Wolfgang,
Ehlenz Richard,
Peseke Klaus,
Meisel Roland
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199518561
Subject(s) - carbene , electrophile , stereoselectivity , surface modification , chemistry , metal , sugar , atom (system on chip) , medicinal chemistry , stereochemistry , organic chemistry , catalysis , computer science , embedded system
Stereoselective functionalization of carbohydrates may be possible with sugar–carbene complexes 1 , in which the C‐1 atom is modified to be a metal‐coordinated carbene. This results in an increase both of the electrophilicity of C‐1 and the acidity of the adjacent CH group. M = Cr, Mo, W, x = 5; M = Fe, x = 4.
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