Synthetic Receptors Based on Vinylogous Sulfonyl Peptides | Zendy

Gennari Cesare | Zendy; Nestler H. Peter | Zendy; Salom Barbara | Zendy; Still W. Clark | Zendy

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Synthetic Receptors Based on Vinylogous Sulfonyl Peptides

Author(s) -

Gennari Cesare,

Nestler H. Peter,

Salom Barbara,

Still W. Clark

Publication year - 1995

Publication title -

angewandte chemie international edition in english

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.831

H-Index - 550

eISSN - 1521-3773

pISSN - 0570-0833

DOI - 10.1002/anie.199517651

Subject(s) - tripeptide , sulfonyl , sequence (biology) , molecule , chemistry , stereochemistry , receptor , combinatorial chemistry , peptide , biochemistry , organic chemistry , alkyl

The tripeptide sequence ( L ‐Pro)‐( D ‐Val)‐( D ‐Pro) is recognized by a tweezerlike molecular receptor constructed from vinylogous sulfonyl peptides (see diagram on the right). The screening of this tweezer molecule against a combinatorial tripeptide library reveals interesting sequence specifities for this new class of receptors. DR = dye molecule (Disperse Red 1), • = polystyrene support.

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