Premium
First Synthesis of 2 H ‐Azepine
Author(s) -
Hamprecht Dieter,
Polborn Kurt,
Steglich Wolfgang
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199514691
Subject(s) - azepine , bicyclic molecule , chemistry , organic chemistry , stereochemistry , combinatorial chemistry
Highly volatile and unstable in the pure form , the 2 H ‐azepine 1 has been synthesized for the first time. This compound is a “spin‐off” from work on the chemistry of azepine alkaloids, which occur in the mushroom Chalciporus piperatus . In addition, a bicyclic product of a surprising Diels–Alder reaction forms in the cyclization step.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom