Premium
A Simple Catalytic Method for the Conversion of Aryl Bromides to Arylamines
Author(s) -
Guram Anil S.,
Rennels Roger A.,
Buchwald Stephen L.
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199513481
Subject(s) - aryl , catalysis , combinatorial chemistry , tin , simplicity , chemistry , boron , broad spectrum , simple (philosophy) , organic chemistry , physics , philosophy , alkyl , epistemology , quantum mechanics
A facile Pd‐catalyzed method for the preparation of a wide variety of aryl amines from aryl bromides and amines has been developed [Eq. (a)]. Noteworthy features of this method include the experimental simplicity, the tin/boron‐free conditions, and the broad spectrum of potential substrates.