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Synthesis of Optically Active Nine‐Membered Ring Lactams by a Zwitterionic Aza‐Claisen Reaction
Author(s) -
Diederich Michel,
Nubbemeyer Udo
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199510261
Subject(s) - optically active , ring (chemistry) , claisen rearrangement , chemistry , stereochemistry , combinatorial chemistry , organic chemistry
Ring expansion with complete chirality transfer takes place in the title reaction in which proline derivatives 1 are converted into lactams 2 under mild conditions.
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