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Total Syntheses of Zaragozic Acid
Author(s) -
Koert Ulrich
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199507731
Subject(s) - total synthesis , stereoselectivity , chemistry , stereochemistry , organic chemistry , catalysis
Three total syntheses of zaragozic acids , a new group of natural products with blood cholesterol lowering properties, were successfully developed within a short time and published almost simultaneously. Convergence, skilled manipulation of protecting groups, and highly stereoselective reactions are the appealing features of these first syntheses of zaragozic acid A (Nicolaou) and zaragozic acid C ( 1 ) (Carreira and Evans).
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