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Photo Electron Transfer Induced Macrocyclization of N ‐Phthaloyl‐ω‐aminocarboxylic Acids
Author(s) -
Griesbeck Axel G.,
Henz Andreas,
Peters Karl,
Peters EvaMaria,
von Schnering Hans Georg
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199504741
Subject(s) - intramolecular force , chemistry , electron transfer , decarboxylation , acceptor , electron acceptor , ring (chemistry) , photochemistry , electron , stereochemistry , medicinal chemistry , organic chemistry , catalysis , physics , condensed matter physics , quantum mechanics
Macrocycles of type 2 with up to 26 ring atoms ( n = 22) are available in very good yields by photo electron transfer (PET) initiated decarboxylation of the anions of N ‐phthaloyl‐ω‐aminocarboxylic acids 1 . The electron transfer is favored as a result of intramolecular K + ‐mediated chelation; however, it can also occur efficiently over larger donor‐acceptor distances.