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The Arndt–Eistert Reaction in Peptide Chemistry: A Facile Access to Homopeptides
Author(s) -
Podlech Joachim,
Seebach Dieter
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199504711
Subject(s) - peptide , chemistry , amino acid , sequence (biology) , combinatorial chemistry , coupling reaction , type (biology) , coupling (piping) , stereochemistry , organic chemistry , biochemistry , materials science , biology , catalysis , ecology , metallurgy
By combination of an Arndt‐Eistert reaction sequence and a peptide coupling , amino acids and peptides can be coupled with a second amino acid or a second peptide to give homopeptides, for example of type 1 . This method has been employed to synthesize up to homohexapeptides.