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Direct Observation of OH Reductive Elimination from Ir III Complexes
Author(s) -
Blum Ofer,
Milstein David
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199502291
Subject(s) - reductive elimination , chemistry , alcohol , elimination reaction , chloride , combinatorial chemistry , iridium , medicinal chemistry , catalysis , organic chemistry
Elimination of alcohols from the Ir III complexes 1 to give 2 is feasible and competes favorably with β‐H elimination to give 3 . This supports proposals that OH reductive elimination is the product‐forming step in industrially important processes such as CO hydrogenation and alcohol homologation. The ancillary π‐donating chloride has a paramount role in this process. L PEt 3 , PMe 3 .