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A Rhodium‐Mediated, Stepwise Trimerization of an Alkyne That Does Not Lead to a Benzene but Selectively to a Hexadienyne Derivative
Author(s) -
Werner Helmut,
Schäfer Martin,
Wolf Justin,
Peters Karl,
von Schnering Hans Georg
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199501911
Subject(s) - rhodium , alkyne , chemistry , derivative (finance) , benzene , ether , crystal structure , metal , medicinal chemistry , stereochemistry , catalysis , crystallography , organic chemistry , financial economics , economics
The coupling of an alkynyl and a butadienyl unit at the rhodium center of 1 is the key step in the selective, stepwise trimerization of methyl propiolate HCCR to hexadienyne 3 with [Rh(η 2 ‐O 2 CMe)(P i Pr 3 ) 2 ] as a metal template. In MgCl 2 in ether, this step occurs almost quantitatively, and the intermediates 1 and 2 were characterized by X‐ray crystal structure analysis.