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A Regioselective Palladium‐Catalyzed Reduction of 3,3‐Heterobimetalated Allylic Acetates— Synthesis and Reactivity of Allylic Bimetallic Compounds
Author(s) -
Lautens Mark,
Delanghe Patrick H. M.
Publication year - 1995
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199424481
Subject(s) - allylic rearrangement , regioselectivity , chemistry , bimetallic strip , palladium , reagent , catalysis , hydride , reactivity (psychology) , organic chemistry , hydrosilylation , medicinal chemistry , combinatorial chemistry , hydrogen , medicine , alternative medicine , pathology
Selective reaction of one of two CSi bonds in 1 with octanal yields 2 . The disilyl compound 1 and also silylstannyl compounds, useful reagents in organic synthesis, could be prepared regioselectively (>99:1) by hydride reduction of allylic acetates.