Premium
Tether‐Directed Remote Functionalization of Buckminsterfullerene: Regiospecific Hexaadduct Formation
Author(s) -
Isaacs Lyle,
Haldimann Richard F.,
Diederich François
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199423391
Subject(s) - surface modification , buckminsterfullerene , yield (engineering) , limiting , chemistry , combinatorial chemistry , fullerene , organic chemistry , materials science , engineering , mechanical engineering , metallurgy
An overall yield of 35% based on C 60 was obtained in the synthesis of hexaadduct 1 . First, bis‐ and trisadducts of C 60 were prepared regiospecifically by tether‐directed remote functionalization. Further functionalization of the trisadduct via a single tetraadduct gave the pseudooctahedral hexaadduct 1 regiospecifically. All intermediates were isolated in pure form without the use of tedious, scale‐limiting HPLC methods.