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Designer Proteins: On the Art of Synthesizing De Novo Metalloproteins
Author(s) -
Kraatz HeinzBernhard
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199420551
Subject(s) - metalloprotein , chemistry , nanotechnology , function (biology) , photosystem ii , redox , biochemistry , materials science , biology , enzyme , photosynthesis , organic chemistry , evolutionary biology
Straddling the boundaries between protein chemistry and coordination chemistry , a promising new field of research has developed. The latest work in this area includes the synthesis of metal‐binding metalloproteins by M. R. Ghadiri et al. and the introduction of redox‐active centers in nonnatural proteins by W. F. DeGrado et al. One can imagine that the concepts behind these syntheses can be extended to, for example, the preparation of metalloproteins that could function as light‐harvesting analogues of the photosystem of green plants.