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5,10,15,20‐Tetra‐ tert ‐butylporphyrin and Its Remarkable Reactivity in the 5‐ and 15‐Positions
Author(s) -
Ema Tadashi,
Senge Mathias O.,
Nelson Nora Y.,
Ogoshi Hisanobu,
Smith Kevin M.
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199418791
Subject(s) - porphyrin , reactivity (psychology) , steric effects , tetra , chemistry , medicinal chemistry , stereochemistry , photochemistry , medicine , alternative medicine , pathology
Owing to the steric bulk of the tert ‐butyl groups , the reactivity of the novel porphyrin 1 , which has a nonplanar macrocyclic framework, deviates distinctly from that of any other known porphyrin. For example, prolonged treatment of 1 in HClO 4 /MeOH leads to formation of 5,15‐dihydroporphyrin (“porphodi‐methene”) 2 .