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Specific Binding of Antibodies to DNA through Combinatorial Antibody Libraries
Author(s) -
Famulok Michael,
Faulhammer Dirk
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199418271
Subject(s) - antibody , phage display , immunization , dna , virology , computational biology , biology , microbiology and biotechnology , immunology , genetics
A much broader range of applications for antibody techniques should result from a new method that allows the production of a large quantity of diverse antibodies without the immunization of animals. Expression on phage surfaces is used to produce antibodies that recognize double‐stranded DNA with specificity. This is but the latest demonstration of the tremendous potential of antibody methods.