Premium
Thianickelacycles by Ring‐Opening Reactions of Cyclic Thioethers and Their Subsequent Carbonylation to Thioesters
Author(s) -
Matsunaga Phillip T.,
Hillhouse Gregory L.
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199417481
Subject(s) - chemistry , carbonylation , yield (engineering) , sulfide , ethylene , nickel , ring (chemistry) , medicinal chemistry , oxidative addition , organic chemistry , photochemistry , carbon monoxide , catalysis , materials science , metallurgy
A functional model for the nickel‐containing CO‐dehydrogenase? Oxidative addition reactions of ethylene sulfide, propylene sulfide, and thietane with nickel complexes like 1 yield thianickelacycles. Formally analogous to the biosynthesis of acetyl coenzyme A, 2 undergoes an insertion reaction with CO followed by reductive elimination of the thiobutyrolactone 3 .