New Cyclic Derivatives of 3′‐Amino‐3′‐deoxy‐adenosine‐5′‐diphosphate, ‐triphosphate, and ‐methylenebis(phosphonate)

A ten‐membered ring system forms part of the adenosine derivative 2 , which can be prepared from triphosphate 1 by an intramolecular condensation with the water‐soluble carbodiimide l‐ethyl‐3‐(3‐dimethylaminopropyl)carbodiimide hydrochloride (EDC); analogous compounds with six‐ and eight‐membered ring systems are accessible from the corresponding mono‐ and diphosphates, respectively. Compounds of this kind are of interest, for instance, as potential enzyme inhibitors. A = adenyl.