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Cyclopropanes by Nucleophilic Attack of Mono‐and Diaryl‐Substituted (η 3 ‐Allyl)palladium Complexes: Aryl Effect and Stereochemistry
Author(s) -
Otte Andreas R.,
Wilde Andreas,
Hoffmann H. M. R.
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199412801
Subject(s) - nucleophile , chemistry , electrophile , deprotonation , palladium , aryl , ring (chemistry) , medicinal chemistry , stereochemistry , organic chemistry , catalysis , alkyl , ion
A series of cis ‐diphenylated cyclopropanes has been introduced into the C‐H acidic position of a range of nucleophiles, for example, deprotonated esters and acid amides, ketones, and sulfones. In these reactions bis[(η 3 ‐l,3‐diphenylallyl)palladium] complexes serve as electrophiles, and products such as 1 form. Quaternary carbon centers exocyclic to the newly formed three‐membered ring are installed with ease.