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Rearrangement and Selective Transmetalation of Bis(pyridyl)methyllithium
Author(s) -
Gornitzka Heinz,
Stalke Dietmar
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199406931
Subject(s) - transmetalation , methyllithium , superbase , chemistry , ligand (biochemistry) , medicinal chemistry , stereochemistry , organic chemistry , catalysis , biochemistry , receptor
The first structurally characterized sodium lithate 1 was obtained by selective transmetalation of [Li{(2‐NC 5 H 4 ) 2 CH}(thf) 2 ] ( 2 ) with the superbase 2 /NaO t Bu. The exchange of only half an equivalent of Li ions in 2 is ascribed to the shape and the basicity of the bis(pyridyl)methyl ligand.