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Continuous Enzymatic Synthesis of 2′‐Deoxythymidine‐5′‐(α‐ D ‐glucopyranosyl)diphosphate
Author(s) -
Zervosen Astrid,
Elling Lothar,
Kula MariaRegina
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199405711
Subject(s) - enzyme , biochemistry , glycosyltransferase , chemistry , atp synthase , carbohydrate synthesis , transferase , nucleotide , gene
The preparation of primary nucleotide sugars like 1 with sucrose synthase, a glycosyl transferase in plants, provides an alternative in enzymatic synthesis to the use of highly specific pyrophosphorylases. In an enzyme membrane reactor a continuous synthesis can be performed on preparative scale.