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Enantioselective, Multigram‐Scale Synthesis with a Catalytic Antibody
Author(s) -
Reymond JeanLouis,
Reber JeanLouis,
Lerner Richard A.
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199404751
Subject(s) - enantioselective synthesis , ketone , organic chemistry , chemistry , enol , catalysis , monoclonal antibody , combinatorial chemistry , antibody , biology , immunology
The enantioselective conversion of the achiral enol ether 1 into the chiral ketone 2 was carried out on a multigram‐scale with a monoclonal antibody (Ab). This procedure requires only conventional laboratory equipment.