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Selective Measurement of the Time‐Dependence of Transient Overhauser Effects in Magnetic Resonance: Applications to Oligonucleotides
Author(s) -
Vincent Sébastien J. F.,
Zwahlen Catherine,
Bodenhausen Geoffrey
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199403431
Subject(s) - two dimensional nuclear magnetic resonance spectroscopy , nuclear overhauser effect , oligonucleotide , duplex (building) , transient (computer programming) , nuclear magnetic resonance , resonance (particle physics) , chemistry , nuclear magnetic resonance spectroscopy , physics , atomic physics , dna , computer science , biochemistry , operating system
The analysis of cross‐ and diagonal‐peak intensities is much faster with the one‐dimensional NMR experiments described here than with two‐dimensional NOESY. This accelerates the comparison of predictions from molecular dynamics calculations with experimental observations, as demonstrated by the example of cytosine‐9 in duplex d(CGCGAATTCGCG) 2 .