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Chiroporphyrins: An Approach to Asymmetric Catalysts with Stereocenters Near the Plane of the Porphyrin Ring
Author(s) -
Veyrat Marc,
Maury Olivier,
Faverjon Frédéric,
Over Diana E.,
Ramasseul René,
Marchon JeanClaude,
TurowskaTyrk Ilona,
Scheidt W. Robert
Publication year - 1994
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199402201
Subject(s) - stereocenter , porphyrin , enantioselective synthesis , pyrrole , catalysis , ring (chemistry) , chemistry , combinatorial chemistry , resolution (logic) , organic chemistry , stereochemistry , computer science , artificial intelligence
Readily available chiral aldehydes and pyrrole provide porphyrins like 1 in a single step. Mn‐Cl derivatives of such compounds are effective catalysts for the enantioselective epoxidation of nonfunctionalized olefins. The design of chiral porphyrin ligands should receive new impetus, since in the synthesis of 1 , the D 2 ‐symmetric isomer is formed preferentially, and time‐consuming resolution is not necessary.