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Palladium‐Catalyzed Arylation of Tetrasubstituted Double Bonds: A Simple Synthesis of Annelated Propellanes
Author(s) -
Dyker Gerald,
Körning Jutta,
Jones Peter G.,
Bubenitschek Peter
Publication year - 1993
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199317331
Subject(s) - palladium , propellane , chemistry , annulation , catalysis , reactivity (psychology) , acenaphthylene , double bond , combinatorial chemistry , organic chemistry , medicinal chemistry , bicyclic molecule , naphthalene , medicine , alternative medicine , pathology
Only two steps are required for the synthesis of the symmetric propellane 1 starting from acenaphthylene. In this conversion the reactivity of strained double bonds is used for palladium‐catalyzed annelation reactions.