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New Developments in the Chemistry of Catalytic Antibodies
Author(s) -
Leumann Christian
Publication year - 1993
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199312911
Subject(s) - chemistry , catalysis , antibody , hydrolysis , combinatorial chemistry , biochemistry , immunology , biology
In the deliberate stereoselective control of reactions and for application in therapy, the chemistry of the antibody catalysts have provided new impulses. Furthermore, recent developments in the field of immunology give rise to the hope that in the future semisynthetic, catalytically active antibodies can be directly prepared by molecular biology so that the classical immunological methods, which require testing on animals, can be replaced. For example, the antibodycatalyzed hydrolysis of cocaine is very promising.