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Domino Reactions of 4‐Ene‐1,2,3‐triol Derivatives
Author(s) -
Mulzer Johann,
Greifenberg Stefan,
Buschmann Jürgen,
Luger Peter
Publication year - 1993
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199311731
Subject(s) - domino , cascade reaction , ene reaction , triol , domino effect , transformation (genetics) , chemistry , combinatorial chemistry , stereochemistry , catalysis , organic chemistry , physics , diol , biochemistry , nuclear physics , gene
Proceeding through at least eight individual steps and ending with a dimerization , the domino cationic transformation of 1 leading to 2 provides a new synthetic approach to bis(furanosides). Domino processes are of current interest in organic synthesis, especially when the reaction requires many single steps and furnishes interesting products with high regio‐ and stereocontrol. a , R 1 = H, R 2 = Me; b = R 1 = R 2 = H; c , R 1 = Et, R 2 = H.