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Peptoids—A New Approach to the Development of Pharmaceuticals
Author(s) -
Kessler Horst
Publication year - 1993
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199305431
Subject(s) - combinatorial chemistry , chemistry , biochemical engineering , monomer , class (philosophy) , computer science , organic chemistry , engineering , artificial intelligence , polymer
N‐substituted oligoglycines, “peptoids” , can be prepared in good yields and high purity without protected monomer building blocks and without deprotection according to Equation (a). This class of compounds should be of great utility in screening for new pharmaceutical lead structures.