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Towards Artificial Ion Channels: Transport of Alkali Metal Ions across Liposomal Membranes by “Bouquet” Molecules
Author(s) -
Pregel Marko J.,
Jullien Ludovic,
Lehn JeanMarie
Publication year - 1992
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199216371
Subject(s) - membrane , liposome , molecule , alkali metal , ion transporter , ion , crown ether , ether , chemistry , synthetic membrane , membrane transport , materials science , polymer chemistry , inorganic chemistry , nanotechnology , organic chemistry , biochemistry
If “bouquet” molecules with a central crown ether or cyclodextrin unit and poly(oxyethylene) or polymethylene arms are built into the membranes of liposomes (as shown in the diagram), Na + and Li + ions can be transported across the membrane. All the results are consistent with a channel transport mechanism.