Premium
DNA Recognition by Hybrid Oligoether–Oligodeoxynucleotide Macrocycles
Author(s) -
Rumney Squire,
Kool Eric T.
Publication year - 1992
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199216171
Subject(s) - oligonucleotide , dna , adduct , chemistry , combinatorial chemistry , biochemistry , organic chemistry
Exceptionally resistant to nucleases , the 1:1 adducts of single‐stranded oligonucleotides and cyclic oligoether–oligonucleotide hybrid compounds form triple‐helical structures. The picture on the right shows schematically the binding in these systems.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom