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Diastereoselective Synthesis of Substituted Cyclohexadienes from Enantiomerically Pure Tricarbonyl(2‐pheny1‐4, 5‐dihydrooxazole)chromium Complexes
Author(s) -
Kündig Ernst Peter,
Ripa Alberto,
Bernardinelli Gérald
Publication year - 1992
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199210711
Subject(s) - chromium , benzene , chemistry , metal , stereochemistry , medicinal chemistry , organic chemistry
Two or, as shown here, three organic groups can be added with high diastereoselectivity to a π bond in benzene [Eq. (a)]. This one‐pot procedure relies on the combined effects of two auxiliaries on the arene: a chiral, σ‐bound heterocycle and a π‐bound metal complex fragment.