Premium
Anti‐Bredt Enol Ethers by Transannular Cyclization of Cycloalkynols
Author(s) -
Detert Heiner,
AnthonyMayer Christina,
Meier Herbert
Publication year - 1992
Publication title -
angewandte chemie international edition in english
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.831
H-Index - 550
eISSN - 1521-3773
pISSN - 0570-0833
DOI - 10.1002/anie.199207911
Subject(s) - enol , chemistry , enol ether , ether , stereochemistry , philosophy , organic chemistry , catalysis
The thermal cycloalkynol–oxabicycloalkene rearrangement provides a new entry to the hitherto poorly known group of anti‐Bredt enol ethers. As an example, above 180°C (!) enol ether 2 is formed quantitatively from 1 . This rearrangement is not limited to strained cycloalkynols.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom